Follicle Stimulating Hormone Receptor (FSHR) Polymorphisms and Polycystic Ovary Syndrome (PCOS)
نویسندگان
چکیده
منابع مشابه
Clomiphene citrate resistance in relation to follicle-stimulating hormone receptor Ser680Ser-polymorphism in polycystic ovary syndrome.
BACKGROUND Clomiphene citrate (CC) response in anovulatory women is difficult to predict and patient-tailored treatment would benefit patient care and time-management. The objective of this study was to evaluate the role of the follicle-stimulating hormone receptor (FSHR) Ser680Ser-polymorphism as a predictor for CC response. METHODS In this retrospective study, 193 patients, diagnosed with p...
متن کاملGenetic variations of follicle stimulating hormone receptor are associated with polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is an endocrine disorder and the criteria are specified by hyperandrogenism, oligomenorrhea or amenorrhea and polycystic ovary morphology. Follicle stimulating hormone (FSH) has effects on oogenesis and follicle development. Several polymorphisms of FSH receptor (FSHR) are related to primary amenorrhea, hypoplastic ovary, and high serum levels of FSH. Thus, an i...
متن کاملTreating Polycystic Ovary Syndrome with TCM Polycystic Ovary Syndrome (PCOS)
Women are usually diagnosed when in their 20s or 30s, but PCOS may also affect teenage girls. The symptoms often begin when a girl's periods start. Women with this disorder often have a mother or sister who has symptoms similar to those of PCOS. The main features are obesity, anovulation or amenorrhea, acne, and excessive hair growth. It is thought to be one of the leading causes of female infe...
متن کاملP-212: Ala 307 Thr Polymorphism of FSHR in Iranian Patients with Polycystic Ovary Syndrome (PCOS)
Background: Follicle stimulating hormone (FSH) receptor plays an important role in FSH signaling during reproductive development. Any changes in FSHR gene is resulted in alteration of amino acid in protein chain, consequence to affect the binding affinity, intracellular signaling and expression levels of FSHR. FSHR polymorphisms can be involved in etiology of many reproductive disorders such as...
متن کاملChromosomes, Dermatoglyphics and Polycystic Ovary Syndrome (pcos)
Keywords: chromosomal dermatoglyphics genetics infertility Polycystic ovarian syndrome PCOS Original Article Aims: To study and co-relate chromosomal abnormalities and dermatoglyphics in infertile female patients with PCOS. Method: 16 cases of PCOS and 16 normal females as controls were selected. Chromosomal study was done using whole blood culture method and GTG Banding in genetic laboratory. ...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2019
ISSN: 1664-2392
DOI: 10.3389/fendo.2019.00023